Cataract Surgery Helps Sleep

Sleep improves with Cataract Surgery:

This study examined sleep development in a group of patients during the first 9 months after cataract extraction. 70 year old men and women (n=407) undergoing cataract surgery at the Department of Ophthalmology, Sundsvall Hospital, Sweden. One month after cataract extraction 28.3% of the men and 37.5% of the women reported poor sleep which is typical of this age group, BUT after 9 months these percentages dropped to 15.8 and 31.4, respectively. The researchers concluded that in elderly persons who have cataracts removed an added benefit may be that sleep is substantially improved especially during the first 9 months after surgery.

source: R. Asplind, et al. Archives of Gerontology and Geriatrics
Volume 38, Issue 1 , Pages 69-75, January 2004.

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92 Year-Old Japanese American with Positive Aging story

Pictured below is Yoshihiro Uchida, 92 years old, born April 1, 1920. Mr Uchida was a Judo Coach for 66 years at San Jose State University, CA. His many accomplishments are balanced by his substantial life challenges. Read his compelling story in:

New York Times, Monday, April 2, 2012, D2

For a quick overview click the NYT video on the right side column of this blog. The “Positive Aging” category.

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Glucose Regulation and Memory

Antonio Convit, Oliver T. Wolf, Chaim Tarshish, and Mony J. de Leon (2003)
Proceedings of the National Academy of Sciences
Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly

Better lifetime management of blood sugar may improve memory in old age and reduce the risk of Alzheimer’s disease. Researchers have linked peripheral glucose regulation and hippocampal function. Their data indicates that improving glucose tolerance will positively impact memory function in later live.

30 normal subjects who were 68.6 ± 7.5 years were evaluated for glucose tolerance. Their memory was also tested. A brain structure known as the hippocampus – key for learning and memory – was measured. Decreased glucose regulation was associated with poor cognitive performance, memory impairments, and atrophy of the hippocampus. The authors concluded that aging brain injury may be due, in part, to impaired glucose metabolism.

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Nicotine Patch and Memory in Later Life

A pilot study of older persons suggests that the nicotine patch may counteract memory loss.

The study was conducted by Dr. Paul Newhouse, director of the Center for Cognitive Medicine at Vanderbilt University School of Medicine. It involved 74 non-smokers with an average age of 76 years who were diagnosed with Minimal Cognitive Impairment (MCI). Half received the nicotine patch @ 15 mg of nictoine per day a day for six months. The other half received a placebo patch. Participants were tested on a battery of memory and cognitive tests before and after receiving the patch. There were very modest memory benefits among those receiving the active nicotine patch versus the placebo group.

The article suggests that nicotine may boost memory by upregulating nicotinic receptors associated with short-term memory consolidation.

Reference: Newhouse P, Kellar K, Aisen P, et al. Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial, Neurology, 2012; 78:91-101.

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Meditation improves Focus

Meditating in Later Life

A report in the journal Psychological Science suggests enhanced brain function through meditating.

Meditation can help sustain attention.

Buddhist monks who regularly meditated perform better than most of us on concentration tests.

In the past five years, other studies have produced evidence that meditation also yields gains in concentration for laypeople who take up the practice and this effect may be magnified in later life.

Strategies to start simple meditation:
1. Find a quiet place.
2. Get in a comfortable position.
2. Empty your mind.
3. Focus on a single thought a word or an idea.
4. Sustain that focus through practice.
5. Return to the same spot, same position, daily for one week.
6. Assess its value afte one week on your level of concentration.

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I’m looking for positive aging ideas

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Music Training and Memory Preservation

Music training may be related to lifespan memory maintenance

Evidence indicates music training may be related to memory preservation in later life. University of Kansas researchers studied 70 healthy adults age 60 to 83 who were divided into groups based on their musical experience. The three groups of study participants included

  • individuals with no musical training
  • persons with 1 to 9 years of training
  • persons with 10 years or more of training.

More than half of the musically trained persons played the piano while approximately a quarter had studied woodwind instruments such as the flute or clarinet. The musicians who had studied the longest performed the best on cognitive tests, followed by the low-level musicians and non-musicians

The results suggest a “strong predictive effect of high musical activity throughout the lifespan on preserved cognitive functioning in advanced age”.

Hanna-Pladdy & MacKay (2011). The relation between instrumental musical activity and cognitive aging, Neuropsychology, , Vol 25, 378-386.

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Common Questions about Memory

Will memorizing lists and speeches improve my memory?

No. If it’s rote repetition, this does nothing, because memory is not a muscle. If you’re using a memory strategy, then practice will improve your strategy skill. If you spend an hour every day on memorizing using mnemonic (method of loci, or pegword strategy), you will indeed become better. In fact, it takes practice before you can effectively use these strategies.

What practice does, is make you better at the memory strategy you practice.

References

Herrmann, D.J. & Searleman, A. 1990. The new multimodal approach to memory improvement. In G. Bower (ed.) Advances in Learning and Motivation, New York: Academic Press.

1. Higbee, Kenneth L. Your memory. How it works and how to improve it. NY: Simon & Schuster, Inc., 1988.

I’ve read that people only use 10% of their brain. Is this true?

This is repeated in many popular books about the brain and memory. It is not clear what evidence exists for such a statement.

Brain activity comes from connections between those billions of neurons. Memory and thought are contained in patterns of activation, not in single neurons. The essence of how the brain works is that the neurons are all connected. The brain is a network. How can a network function if significant portions of it are in disuse?

I have more trouble remembering words and names. Is this Alzheimer’s?

As we get older, it is normal to experience more  memory blocks for names of objects and people.Not, interestingly enough, for abstract words.

When you were in your twenties, you had many memory blocks — occasions when something is ‘on the tip of my tongue’. But this is not because you had Alzheimer’s. It is because memory blocks occur for everyone. They become more noticeable in old age because you worry about them more.

Why do I have trouble remembering people’s names?

The principal reason for the common tendency to forget people’s names is simple – we don’t pay enough attention when we hear them. But why are names so much harder than other things to remember? It’s because we feel so bad when we forget a name?

The main tenet of memory is that well-connected information is easy to remember. The more connections a piece of information has, the more likely you are to recall it. But what connections does a name have with a person?  Names are arbitrary. You have to make a special effort to create a meaningful connection for it.

Does playing tapes while you’re asleep help you learn?

Not really.

There are circumstances in which learning can occur while you’re asleep. Here are some fact:

  • The information to be learned cannot require understanding – it is thus useful for memorizing rather than true learning.
  • You must be in the right stage of sleep – a light, drowsy state.
  • The ‘sleep learning’ must augment ordinary learning, it can’t take the place of it.

References

Baddeley, Alan.Your memory: A user’s guide. (2nd ed.) London: Penguin Books, 1994.

Higbee, Kenneth L. Your memory. How it works and how to improve it. NY: Simon & Schuster, Inc., 1988.

Do mnemonic strategies really work?

Certainly. Mnemonic strategies work. However, for the most part they are strategies that require practice to master. For example, to use the method of loci requires at least half an hour of pratice.  If you have a specific need to remember lots of names, mastering the face-name association strategy is probably worth it.

Is everything we ever experienced recorded somewhere in our brain?

No.The origin of this belief seems to lie in the work done by a Canadian surgeon, Wilder Penfield, in the 1950s.  The brain itself has no sensors for pain, Penfield (with the patients’ consent) used operations on the brain to investigate the storage of memory. While the brain was exposed, and the patients fully conscious, Penfield stimulated different parts of the cortex electrically. In most cases, the patients had no sensation or experience to report, but occasionally they would claim to re-experience very vivid scenes from their past.

This was taken by many at the time to demonstrate that memory works like a camera – that every detail is experienced, and is recorded in the brain, and nothing is truly lost. However, it now seems clear that the interpretation of these results was over simplistic.

References

Greenfield, Susan. The human brain: A guided tour. London: Weidenfeld & Nicolson, 1997.

Schacter, Daniel L. Searching for memory: The Brain, the Mind, and the Past. NY: Basic Books, 1996.

Why do we forget?

Forgetting, it can be argued, is adaptive. The ability to abstract general rules from specific instances is far more useful than the ability to remember every specific detail, and the one seems to preclude the other1.

There is no evidence that information stored in memory can actually disappear (except of course when the brain is physically damaged). However, when information is reaches long-term memory store, it passes through “working memory”. Information can be lost in working memory. If the information doesn’t make it through the encoding process (when it is “in” working memory), then it will not enter exist in long-term memory. You may have a vague feeling that such information exists but you won’t be able to recall details.

Forgetting occurs because:

  • information was never properly encoded in the first place, or
  • you can’t find it

1. Schacter, Daniel L. Searching for memory: The Brain, the Mind, and the Past. NY: Basic Books, 1996.

Am I too old to learn?

No.

It is true that memory performance begins to decline after the mid-forties, but the effects of age on memory are complex, as memory itself is complex. It is not true that a particular seventy-year-old necessarily has a ‘worse’ memory than his thirty-year-old grandson. It is probably true that the grandson remembers most information with less effort than his grandfather. It is not true that the grandfather can’t match his grandson’s performance with more effort – or more cunning. If one is skilled at specific memory strategies, and the other isn’t, this can be more important than any age differences.

Older adults have a big advantage to offset the slowness that comes with increasing age. Experience. A good memory is an organized memory, is a richly connected memory. With a wealth of experience, an older person has the potential for many connections. With the right strategies, such rich connectivity can make remembering very efficient.

References

Baddeley, Alan.Your memory: A user’s guide. (2nd ed.) London: Penguin Books, 1994.

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Ideas for Memory Maintenance

 

Preventing memory loss

(This article is excerpted from the Harvard Health Publications Special Health Report “Improving Memory: Understanding and Preventing Age-Related Memory Loss”. For more information or to order, please go to http://health.harvard.edu/IM.)

No matter what your age, it’s not too late to take steps to prevent memory loss. A good place to start is with the strategies for improving your memory described in this report.

Preventive steps

Research shows that the following strategies may help preserve your memory.

Exercise

Physical fitness and mental fitness go together. People who get regular vigorous exercise also tend to stay mentally sharp in their 70s and 80s. There are several ways in which exercise might benefit your memory.

First, it’s good for the lungs, and people whose memories and mental acuity remain strong in old age characteristically have good lung function.

Second, exercise helps reduce the risk for diabetes, high cholesterol, high blood pressure, and stroke – illnesses that can lead to memory loss.

Third, animal research has shown that exercise increases the level of neurotrophins, substances that nourish brain cells and help protect them against damage from stroke and other injuries.

The people in the MacArthur study whose mental functions remained strong were active almost daily. A study from Case Western Reserve University School of Medicine concluded that individuals who exercised – by walking or by engaging in physically active hobbies, such as gardening – had a lower risk for Alzheimer’s disease. So experts recommend that you build physical activity into your daily routine. Here are some examples:

  • When possible, walk instead of driving or riding.
  • Set aside time each day for exercise.
  • Use the stairs instead of elevators.
  • Exercise at home, possibly with an exercise video.
  • Plant a garden.
  • Take an exercise class or join a health club.
  • Swim regularly, if you have access to a pool or beach.
  • Learn a sport that requires modest physical exertion, such as tennis.
Physical activity keeps both your body and your mind in shape.

Keep learning

In the MacArthur study, the characteristic that correlated most strongly with good mental functioning in old age was a person’s level of education. Experts think that advanced education may help keep memory strong by getting people into the habit of being mentally active.

Some people continue their education with adult education classes or advanced degrees even in late adulthood.

Reading regularly, keeping up with current affairs, learning a new hobby, and playing challenging games all exercise your mind.

Don’t smoke

Studies show that smokers don’t remember people’s names and faces as well as nonsmokers do. No one knows whether smoking directly impairs memory or is merely associated with memory loss because it causes illnesses that contribute to memory loss. Smoking is especially common among people who are depressed, and depression weakens the memory. In addition, smoking increases the risk for stroke and hypertension, two other causes of memory impairment.

Maintain a healthy diet

A healthful diet rich in fruits and vegetables as well as healthy fats from fish, nuts, and whole grains is vital in maintaining the health not just of your body but of your brain as well.

Avoiding saturated fats (in meat and dairy) and trans fats (in commercial products with partially hydrogenated oils) will help keep your arteries clear and cholesterol levels healthy, and that in turn will decrease your chances of stroke, including the small undetectable ones that can damage brain function.

Avoid excess calories to maintain a normal weight; this lowers your risk for illnesses such as diabetes and hypertension, which can impair your memory.

Eating a lot of fruits and vegetables can be especially beneficial because many are good sources of antioxidants, nutrients that may protect against diseases and age-related deterioration throughout the body.

Nutritious foods such as fruits, vegetables, and nuts are essential for keepking your brain healthy.

Get a good night’s sleep

Sleep is essential for memory consolidation as well as overall health. Although people vary widely in their individual sleep needs, research suggests that six to eight hours of sleep a night is ideal.

People with breathing problems during sleep, such as obstructive sleep apnea, can sleep for 10 hours per night but never feel refreshed in the morning. Of course, for some people, getting a good night’s sleep is easier said than done, especially becaus e insomnia becomes more common with age.

Try the following:

  • Establish and maintain a consistent sleep schedule and routine. Go to bed at the same time each night and wake up at the same time each morning.
  • Plan to do your most vigorous exercise early in the day. Exercising in the hours immediately before bedtime causes physiological changes that interfere with sleep. Exercising in the morning, on the other hand, enhances your alertness when you need it most – at the beginning of the day.
  • Avoid coffee and other sources of caffeine after midmorning, because caffeine is a stimulant that can keep you awake for hours afterward.
  • Avoid napping during the daytime. Napping can disrupt your natural sleep cycle and prevent you from feeling tired enough to fall asleep at night.
  • Don’t take sleeping pills unless nothing else works. Like sleep deprivation, sleeping pills can cause memory loss.
  • Try drinking warm milk before bedtime. Some people find that it helps them feel sleepy. Milk contains tryptophan, a chemical that may help you relax.
  • If you’re still awake after about 20 minutes in bed, get up and read awhile to help yourself relax.

Cultivate social support

The MacArthur researchers described a study in a nursing home in which residents were asked to do a simple jigsaw puzzle. During a practice session:

One group was given verbal encouragement by one of the experimenters as they practiced doing the jigsaw puzzle.

The second group was told how to do the jigsaw puzzle.

The third group got no social support or how-to advice.

Later, those in the group given encouragement did better than they had during the practice session. The people who had been told what to do had more trouble during the test than they’d had in the practice session. And those who had received neither encouragement nor advice did neither better nor worse.

Being too quick to show a person what to do can lower that person’s self-confidence and motivation to figure things out. In other words, it can instill a sense of helplessness.

Troubleshooting memory problems: Common memory lapses and strategies to overcome them

What you forget How to remember better
Names When you meet someone for the first time, use his or her name in coversation.
Think about whether you like the name.
Think of people you know well who have the same name.
Associate the name with an image, if one comes to mind. For example, link the name Sandy with the image of a beach.
Write the person’s name down in your memory notebook, personal organizer, or adress book.
Where you put things Always put things you use regularly, such keys and eyeglasses, in the same place.
For other objects, repeat aloud where you put them.
As you put an object down, make a point of looking at the place where you put it.
If you still don’t think you’ll remember, write down in your memory notebook or personal organizer where you put the object.
What people tell you Ask someone to repeat what he or she just said.
Ask the person to speak slowly; that way, you’ll be able to concentrate better.
Repeat to yourself what the person said and think about its meaning.
If the information is lengthy or complicated (such as advice from your doctor), use a small cassette recorder or take notes while the person is talking.
Appointments Write them down in an appointment book, in a calendar that you look at daily, or in your personal organizer.
Things you must do Write them down in your personal organizer or calendar.
Write yourself a note and leave it in a place where you’ll see it (for instance, on the kitchen table or by the front door).
Ask a friend or relative to remind you.
Leave an object associated with the task you must do out in a prominent place at home. For example, if you want to order tickets to a play, leave a newspaper ad for the play near your telephone.
If you must do something at a particular time (such as take medicine), set an alarm.
Adapted with permission from Winifred Sachs, Ed.D., Center for Cognitive Remediation and Treatment, Beth Isreal Deaconess Medical Center.
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Curiosity Predicts Longevity

Curiosity and Mortality in Aging Adults: A 5-Year Follow-up of the Western Collaborative Group Study

Gary E. Swan & Dorit Carmelli (SRI International)

Previous research suggests that curiosity in older people is associated with the maintenance of health of the aging central nervous system. The present investigation examined the relationship of curiosity in 1,118 community-dwelling older men and survival over a 5-year follow-up. Curiosity was measured when the subjects were an average age of 70.6 years. Levels of trait and state curiosity at initial examination were higher in survivors than in those who subsequently died. After adjustment for other risk factors, the state curiosity-mortality association remained significant  The present study is the first to identify a predictive role for curiosity in the longevity of older adults.

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